The HTAi 2026 Annual Meeting invites the global HTA community to explore this transformative role. By bridging sectors, informing priority-setting, and engaging stakeholders—including patients and communities—HTA can influence how care models evolve, resources are allocated, and health systems adapt to complex challenges. This meeting provides a critical platform to imagine and act on HTA’s potential to create resilient, inclusive, and future-ready health systems. The future of HTA—and our health systems—depends on the choices we make today.